Of course, science fiction is not just for books and movies--it also plays an important role in video games. In particular, I'd like to point out the Metroid franchise as a longstanding science fiction game series.
Metroid first came out in America on Aug. 15, 1987, for the Nintendo Entertainment System and hit huge success with Super Metroid for the Super NES (which came out in the U.S. on April 18, 1984). Twenty-three years later since the first game, the newest game in the series, Metroid: Other M, will be coming out for the Nintendo Wii this Aug. 31. It looks great and is expected to go deeper into the storyline. For more information about the games, visit www.metroid-database.com (the website has about everything you want to know about Metroid).
Check out the two videos for the game. The first one was a trailer revealed at the 2010 E3 event (focusing on the game play) while the second one is from the 2009 E3 event (with both story and game-play elements). And just just because I love the video, I threw in a trailer for the Metroid Prime game that came out Nov. 8, 2002 (although the CG is not in the game, unfortunately). Enjoy!